The Exchange 2003 mailbox servers may run out of available memory. When this problem occurs, the Exchange server stops responding, and the following event message is logged in the Application log.
Event Type: Warning
Event Source: MSExchangeIS
Event Category: Performance
Event ID: 9582
Description: The virtual memory necessary to run your Exchange server is fragmented in such a way that performance may be affected. It is highly recommended that you restart all Exchange services to correct this issue.